Source registry
Sources used on Octenidine.org
These references help distinguish substance identity, regulatory context, safety information, clinical evidence,
product documents, and literature searches.
- Last reviewed
- 2026-05-07
- Reviewed by
- Octenidine.org Editorial Team
Identity, regulatory, and safety
- Publisher
- PubChem, National Library of Medicine
- Source type
- official chemical substance record
- Last checked
- 2026-05-06
- Does not establish
- clinical effectiveness claims; product-specific label instructions; jurisdiction-specific approval claims
Supports names, identifiers, structure, formula, synonyms, and links to other official substance records. Identity, regulatory, and safety
- Publisher
- U.S. Food and Drug Administration Global Substance Registration System
- Source type
- official substance identity record
- Last checked
- 2026-05-06
- Does not establish
- FDA approval claims; clinical benefit claims; consumer use instructions
Supports UNII, preferred substance name, formula, and synonym mapping. The GSRS page states that UNII availability does not imply regulatory review or approval. Identity, regulatory, and safety
- Publisher
- European Chemicals Agency
- Source type
- official chemical substance information
- Last checked
- 2026-05-06
- Does not establish
- human clinical effectiveness; medical product authorization; finished-product directions
Supports EU chemical identity, EC/CAS linkage, and chemical regulatory context when the exact page supports the statement. Identity, regulatory, and safety
- Publisher
- European Medicines Agency
- Source type
- official veterinary regulatory assessment page
- Last checked
- 2026-05-06
- Does not establish
- human antiseptic approval claims; consumer treatment guidance; general efficacy claims
Supports the EMA veterinary maximum-residue-limit context and related regulatory history. Identity, regulatory, and safety
- Publisher
- European Medicines Agency
- Source type
- official orphan designation page
- Last checked
- 2026-05-06
- Does not establish
- approval or authorization claims; neonatal treatment guidance; evidence of clinical effectiveness
Supports the narrow orphan-designation history and the EMA page's own development-stage language. Evidence synthesis
- Publisher
- NCBI Bookshelf
- Source type
- health technology evidence report
- Last checked
- 2026-05-06
- Does not establish
- chemical identity; product label instructions; claims outside wound-cleanser evidence reviewed in the report
Supports cautious wound-care evidence summaries and limitations, including when evidence is mixed or not statistically significant. Evidence synthesis
- Publisher
- PubMed Central
- Source type
- peer-reviewed narrative review
- Last checked
- 2026-05-06
- Does not establish
- clinical recommendations; product substitution guidance; claims outside the reviewed clinical settings
Supports clinical-evidence summaries and discussion of evidence gaps while preserving the review's limitations. Primary literature
- Publisher
- Antimicrobial Agents and Chemotherapy / PubMed Central
- Source type
- primary microbiology study
- Last checked
- 2026-05-06
- Does not establish
- modern clinical effectiveness claims; human treatment instructions; finished-product label claims
Supports historical and microbiology context when in vitro or model limits remain clear. Primary literature
- Publisher
- PubMed Central
- Source type
- primary clinical microbiology study
- Last checked
- 2026-05-06
- Does not establish
- site-wide comparative superiority claims; consumer instructions; claims beyond susceptibility outcomes and study context
Supports susceptibility and study-context discussion when design and limitations are described. Evidence synthesis
- Publisher
- Cochrane
- Source type
- Cochrane evidence synthesis
- Last checked
- 2026-05-07
- Does not establish
- wound-care instructions; product-specific label claims; claims outside venous leg ulcer cleansing evidence
Supports cautious venous leg ulcer wound-cleansing evidence limits and uncertainty language. Evidence synthesis
- Publisher
- Antibiotics / MDPI
- Source type
- systematic review
- Last checked
- 2026-05-07
- Does not establish
- treatment instructions; product rankings; claims outside chronic-wound antiseptic evidence
Supports chronic-wound antiseptic evidence summaries when octenidine limitations and comparator details stay visible. Primary literature
- Publisher
- International Wound Journal / PubMed
- Source type
- primary randomized controlled trial record
- Last checked
- 2026-05-07
- Does not establish
- general wound-care recommendations; claims about octenidine dihydrochloride alone; claims outside chronic venous leg ulcers and the studied product context
Supports exact venous leg ulcer study context when formulation, comparator, and outcome limits are retained. Primary literature
- Publisher
- International Journal of Antimicrobial Agents / ScienceDirect
- Source type
- primary mechanism study
- Last checked
- 2026-05-07
- Does not establish
- patient outcome claims; clinical effectiveness claims; finished-product label instructions
Supports mechanism language for E. coli and model membrane systems when in vitro limits remain explicit. Primary literature
- Publisher
- Biophysical Journal / PubMed
- Source type
- primary membrane biophysics study
- Last checked
- 2026-05-07
- Does not establish
- clinical superiority claims; patient outcome claims; broad resistance or safety conclusions
Supports model-membrane mechanism discussion and cautions against oversimplified electrostatic explanations. Identity, regulatory, and safety
- Publisher
- Occupational Safety and Health Administration
- Source type
- official hazard communication standard appendix
- Last checked
- 2026-05-07
- Does not establish
- clinical safety claims; supplier quality claims; non-U.S. legal advice or workplace compliance advice
Supports U.S. SDS format and section-structure discussion for hazard communication context. Identity, regulatory, and safety
- Publisher
- European Chemicals Agency
- Source type
- official safety data sheet explainer
- Last checked
- 2026-05-07
- Does not establish
- clinical effectiveness claims; product-specific label claims; supplier selection or procurement advice
Supports plain-language SDS role and workplace hazard communication boundaries. Identity, regulatory, and safety
- Publisher
- MedlinePlus / National Library of Medicine
- Source type
- official consumer health information guidance
- Last checked
- 2026-05-07
- Does not establish
- octenidine-specific clinical claims; product label instructions; regulatory status claims
Supports consumer guidance on checking source ownership, purpose, evidence, review, and update dates. Identity, regulatory, and safety
- Publisher
- U.S. Food and Drug Administration
- Source type
- official consumer label-reading guidance
- Last checked
- 2026-05-07
- Does not establish
- claims that octenidine products are U.S. OTC drugs; product-specific use instructions; clinical effectiveness claims
Supports general U.S. OTC Drug Facts label concepts such as active ingredient, warnings, directions, and other information. Identity, regulatory, and safety
- Publisher
- Health Resources and Services Administration
- Source type
- official U.S. poison-control public guidance
- Last checked
- 2026-05-07
- Does not establish
- non-U.S. emergency routing; product-specific treatment instructions; clinical safety claims for routine use
Supports U.S.-specific poison-help routing and information to have ready during a poison-center call. Identity, regulatory, and safety
- Publisher
- MedlinePlus / National Library of Medicine
- Source type
- official patient communication guidance
- Last checked
- 2026-05-07
- Does not establish
- octenidine-specific clinical claims; product-specific use instructions; emergency exposure management
Supports patient preparation, question lists, note-taking, and follow-up communication guidance. Identity, regulatory, and safety
- Publisher
- Agency for Healthcare Research and Quality
- Source type
- official patient engagement guidance
- Last checked
- 2026-05-07
- Does not establish
- octenidine-specific clinical claims; product-specific use instructions; regulatory status claims
Supports patient question-asking and comprehension language while keeping product-specific advice separate. Identity, regulatory, and safety
- Publisher
- U.S. Food and Drug Administration
- Source type
- official topical antiseptic product class page
- Last checked
- 2026-05-07
- Does not establish
- octenidine-specific clinical claims; finished-product directions; claims outside the product and jurisdiction named by the source
Supports general topical antiseptic product-category context while keeping product-specific claims separate. Identity, regulatory, and safety
- Publisher
- U.S. Food and Drug Administration
- Source type
- official drug-label and approval terminology glossary
- Last checked
- 2026-05-07
- Does not establish
- octenidine-specific clinical claims; product-specific label instructions; non-U.S. regulatory conclusions
Supports general U.S. drug-label and approval terminology when exact product claims are kept separate. Identity, regulatory, and safety
- Publisher
- U.S. Food and Drug Administration
- Source type
- official off-label use explainer
- Last checked
- 2026-05-07
- Does not establish
- octenidine-specific product advice; clinical recommendations; non-U.S. regulatory conclusions
Supports general off-label-use terminology and the distinction between approved labeling and other uses. Literature discovery
- Publisher
- National Library of Medicine
- Source type
- literature discovery search
- Last checked
- 2026-05-06
- Does not establish
- article claims without opening and reviewing individual records; evidence grading; regulatory claims
Provides a literature discovery route; claim support belongs with the individual reviewed articles rather than the search page.